| Test code: | 1513 |
| Type of disorder: | Neuromuscular Disorders |
| Disease(s) tested for: | Myasthenia Gravis (MG) |
| Profiles that contain this test: | Acetylcholine Receptor Binding Antibody with Reflex to MuSK Antibody Myasthenia Gravis Panel 2 with Reflex to MuSK Antibody |
| Clinical Significance: | Myasthenia Gravis (MG) is an autoimmune neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. AChR binding autoantibodies are diagnostic of MG, and are found in 85% to 90% of MG patients. This assay aids in the differential diagnosis of conditions with MG-like muscle weakness and in monitoring therapeutic response. If binding antibodies are negative, assays for modulating and blocking antibodies should be considered. |
| Methodology: | Radioimmunoassay |
| Reference Range: | <=0.30 nmol/L |
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
| CPT: | 86041(1) |
Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
| Specimen Type: | Serum |
| Specimen Stability: | |
| Specimen Requirements: | 2 mL (0.5 mL minimum) serum in a Red-top tube or Serum Separator Tube (SST) |
| Instructions: | Allow blood to clot at room temperature. Serum should be separated from cells within one hour. |
| Transport Temperature: | Room temperature |
| Set-up/Analytic Time: | 7-14 days |
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