| Test code: | 1510 |
| Type of disorder: | Neuromuscular Disorders |
| Disease(s) tested for: | Myasthenia Gravis (MG) |
| Tests included: | Acetylcholine Receptor Binding Antibody
MuSK Antibody Test |
| Special Notes: | Reflex Criteria: If the Acetylcholine Receptor Binding Antibody is negative then the MuSK Antibody Test will be performed at additional charge (CPT code: 83519) |
| Clinical Significance: | Anti-acetylcholine receptor binding antibodies (anti-AChR) are associated with Myasthenia Gravis (MG) and are found in approximately 85% of MG patients. Approximately 8% to 10% of all MG cases and 20% to 50% of generalized MG cases who lack anti-AChR antibodies have autoantibodies against muscle-specific kinase (anti-MuSK). |
| Methodology: |
Radioimmunoassay
|
| Reference Range: | See Laboratory Report |
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
| Specimen Type: | Serum |
| Specimen Stability: |
Room temperature: 72 hours, Refrigerated: 14 days, Frozen: 30 days, |
| Specimen Requirements: |
2 mL (0.5 mL minimum) serum in a Red-top tube or Serum Separator Tube (SST) |
| Instructions: | Allow blood to clot at room temperature. Serum should be separated from cells within one hour. |
| Transport Temperature: | Refrigerated |
| Set-up/Analytic Time: | 7-14 days |
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