VGKC Antibody Test

Test Code
485

Test Details


Test code:485
Type of disorder:Paraneoplastic and Other Antibody Disorders of the CNS
Disease(s) tested for:Paraneoplastic Neurological Syndrome, Autoimmune Encephalitis, Neuromyotonia
Profiles that contain this test:NeoComplete Paraneoplastic Evaluation with Recombx®
NeoEncephalitis Paraneoplastic Evaluation with Recombx®
Neuromyotonia Evaluation

Technical Information


Clinical Significance:Detection of antibodies to voltage gated potassium channels (VGKC)

Typical Presentation: Acute or subacute onset symptoms of limbic encephalitis including confusion/dementia, depression/anxiety and/or seizures or hallucinations, peripheral nerve hyperexcitability, acquired neuromyotonia, autonomic dysfunction
Methodology: Radioimmunoassay
Reference Range:<112 pmol/L

CPT Coding


The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

CPT:83519(1)

Specimen Requirements


Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.

Specimen Type:Serum
Specimen Stability: Room temperature: 72 hours, Refrigerated: 28 days, Frozen: 1 year,
Specimen Requirements: 2 mL (0.5 mL minimum) serum in a Red-top tube or Serum Separator Tube (SST)
Instructions:Serum must be separated from whole blood within 48 hours of collection.

Shipping Considerations


Transport Temperature:Refrigerated
Set-up/Analytic Time:7-10 days

Additional Resources

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