VGCC Type P/Q Autoantibody Test (LEMS)

Test Code
475

Test Details


Test code:475
Type of disorder:Paraneoplastic and Other Antibody Disorders of the CNS
Disease(s) tested for:Lambert-Eaton Myasthenic Syndrome
Profiles that contain this test:NeoComplete Paraneoplastic Evaluation with Recombx®

Technical Information


Clinical Significance:Anti-voltage-gated calcium channels (VGCC), P/Q type are found in patients with muscle weakness, sometimes accompanied by autonomic nervous system dysfunction or cerebellar ataxia. Less commonly paraneoplastic cerebellar degeneration.

Typical Presentation: Muscle weakness, sometimes accompanied by autonomic nervous system dysfunction or cerebellar ataxia. Less commonly paraneoplastic cerebellar degeneration.
Methodology: Radioimmunoassay
Reference Range:Negative < or = 120; Borderline 121-200; Positive >200

CPT Coding


The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

CPT:86596

Specimen Requirements


Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.

Specimen Type:Serum
Specimen Stability: Room temperature: 72 hours, Refrigerated: 28 days, Frozen: 1 year,
Specimen Requirements: 2 mL (0.5 mL minimum) serum in a Red-top tube or Serum Separator Tube (SST)
Instructions:Serum must be separated from whole blood within 48 hours of collection.

Shipping Considerations


Transport Temperature:Refrigerated
Set-up/Analytic Time:7-10 days

Additional Resources

Letters of Medical Necessity

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