| Test code: | 4724 |
| Type of disorder: | Paraneoplastic and Other Antibody Disorders of the CNS |
| Disease(s) tested for: | Paraneoplastic Neurological Syndrome, Stiff Person Syndrome |
| Tests included: | GAD65 Neurological Syndrome Antibody Test Recombx® Amphiphysin Autoantibody Test Recombx® CV2 Autoantibody Test Recombx® Hu Autoantibody Test Recombx® MaTa Autoantibody Test Recombx® Ri Autoantibody Test Recombx® Yo Autoantibody Test Recombx® Zic4 Autoantibody Test |
| Clinical Significance: | Anti-CV2, anti-Hu, anti-Ma, anti-Ta, anti-Ri, anti-Yo, anti-Zic4 antibodies, and anti-GAD65 are found in patients with acute or subacute symptoms of cerebellar degeneration including gait ataxia, nystagmus and/or dysarthria, and opsoclonus/myoclonus. This semi-quantitative assay may be useful in monitoring therapeutic responses in select cases. |
| Methodology: | Automated Nanoliter Scale Immunoassay, ELISA |
| Reference Range: | See Laboratory Report |
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
| CPT: | 83520(7), 86341(1) |
Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
| Specimen Type: | Serum |
| Specimen Stability: | Room temperature: 72 hours, Refrigerated: 28 days, Frozen: 28 days, |
| Specimen Requirements: | 2 mL (0.5 mL minimum) serum in a Red-top tube or Serum Separator Tube (SST) |
| Instructions: | Serum must be separated from whole blood within 48 hours of collection. |
| Transport Temperature: | Refrigerated |
| Set-up/Analytic Time: | 7-10 days |
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