| Test code: | 109 |
| Type of disorder: | Dementia |
| Disease(s) tested for: | Alzheimer's Disease |
| Profiles that contain this test: | ADmark® Alzheimer’s Evaluation |
| Informed Consent Required: | This test requires physician attestation that patient consent has been received |
| Special Notes: | Athena does not perform ApoE testing for individuals under the age of 18. Pre-test and post-test genetic counseling is strongly recommended. |
| Patents: | 5,508,167 5,716,828 6,027,896 |
| Clinical Significance: | Detection of ApoE2, E3, E4 alleles
Typical Presentation: Dementia |
| Methodology: |
Restriction Fragment Length Polymorphism (RFLP)
|
| Reference Range: | Presence of ApoE2, E3, E4 alleles |
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
| Specimen Type: | Whole blood |
| Specimen Stability: |
Room temperature: 10 days, Refrigerated: 10 days, Frozen: 90 days, |
| Specimen Requirements: |
8 mL (6 mL minimum) whole blood collected in two (lavender-top) EDTA tubes. |
| Instructions: | Higher blood volumes ensure adequate DNA quantity, which varies with WBC, specimen condition, and need for confirmatory testing. |
| Transport Temperature: | Room temperature |
| Set-up/Analytic Time: | 7-14 days |
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