| Test code: | 112 |
| Type of disorder: | Multiple Sclerosis |
| Disease(s) tested for: | Multiple Sclerosis |
| Clinical Significance: | Detection of neutralizing antibodies to interferon-beta
Typical Presentation: Multiple Sclerosis patients treated with interferon-beta.
Indications for testing: Individuals on interferon-1 therapy, both 1a and 1b
|
| Methodology: |
Viral Cytopathic Effect Assay
|
| Reference Range: | <1:20 |
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
| Specimen Type: | Serum |
| Specimen Stability: |
Room temperature: 72 hours, Refrigerated: 28 days, Frozen: 6 months, |
| Specimen Requirements: |
2 mL (0.5 mL minimum) serum in a Red-top tube or Serum Separator Tube (SST) |
| Instructions: | Sample needs to be collected either before treatment with interferon or more than 24 hours following the most recent dose. Patient should not be on steroid therapy for at least two weeks prior to testing. Serum must be separated from whole blood within 48 hours of collection. |
| Transport Temperature: | Refrigerated |
| Set-up/Analytic Time: | 14-21 days |
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